Ketamine suppresses REM sleep and markedly increases EEG gamma oscillations in the Wistar Kyoto rat model of treatment-resistant depression
Behavioural Brain Research 449, 114473
Sandor Kantor, PhD
Electrophysiology
Consulting
Services
Your Translational EEG Partner for CNS Drug Development
Bridging preclinical and clinical development with 20+ years of expertise in neurophysiological biomarkers, pharmaco-EEG, and CNS drug discovery.
About
I am a translational neuroscientist with over 20 years of experience bridging basic research and drug development. My career has spanned prestigious academic institutions including Harvard Medical School and the University of Cambridge, as well as leadership roles in the pharmaceutical industry.
As former Scientific Director at a multinational preclinical CRO, I led international teams delivering neurophysiological biomarker programmes for major pharmaceutical companies and innovative biotech firms. My expertise centres on EEG methodology, pharmaco-EEG profiling, and the design of translational studies that de-risk CNS drug development.
I hold a PhD in Clinical Medicine and have authored over 20 peer-reviewed publications in leading journals including Brain, Sleep, and Neurotherapeutics. My research has been supported by over £270,000 in competitive funding.
20+
Years Experience
20+
Publications
£270K+
Research Funding
3
Continents
Services
I offer specialist consulting services tailored to pharmaceutical companies, biotech firms, and academic research groups working in CNS drug discovery and neuroscience research.
EEG Biomarker Strategy & Analysis
Development and validation of EEG-based biomarker strategies for CNS drug programmes. Expert analysis of quantitative EEG data, spectral power, coherence, and event-related potentials to support regulatory submissions and go/no-go decisions.
Pharmaco-EEG Study Design
End-to-end design of pharmaco-EEG studies from protocol development through to data interpretation. Dose-response characterisation, sleep-wake profiling, and seizure liability assessment in preclinical and translational models.
Preclinical-to-Clinical Translation
Strategic guidance on bridging preclinical findings to clinical development. Translational biomarker selection, cross-species comparison of neurophysiological endpoints, and evidence-based recommendations for first-in-human study design.
AI/ML in Neuroscience
Application of machine learning and artificial intelligence approaches to neurophysiological data analysis. Automated signal processing, pattern recognition in EEG datasets, and development of predictive models for drug response classification.
CNS Drug Discovery Consulting
Strategic and scientific advisory services spanning target validation, lead optimisation support, and preclinical development planning for CNS programmes. Therapeutic area expertise includes neurodegeneration, sleep disorders, depression, and neuropsychiatric conditions.
EEG Systems Design & Implementation
Consulting on the selection, setup, and optimisation of EEG recording systems for research and drug discovery environments. Hardware configuration, electrode montage design, signal quality assurance, and standard operating procedure development.
Selected Publications
A selection of peer-reviewed publications from over 20 papers spanning neurophysiology, sleep research, neurodegeneration, and CNS pharmacology.
Chronic paroxetine treatment prevents the emergence of abnormal EEG oscillations in Huntington's disease mice
Neurotherapeutics 4, 1120–1133
A single dose of hypnotic corrects sleep and EEG abnormalities in symptomatic Huntington's disease mice
Neuropharmacology 105, 298–307
Effects of the fatty acid amide hydrolase inhibitor URB597 on coping behavior under challenging conditions in mice
Psychopharmacology 231, 593–601
Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice
Sleep 36, 1129–1138
Progressive sleep and electroencephalogram changes in mice carrying the Huntington's disease mutation
Brain 136, 2147–2158
Get in Touch
Interested in discussing a project or exploring how I can support your research programme? I'd welcome the opportunity to hear about your needs.
Based in the United Kingdom. Available for remote consulting worldwide.