Ketamine suppresses REM sleep and markedly increases EEG gamma oscillations in the Wistar Kyoto rat model of treatment-resistant depression
Behavioural Brain Research 449, 114473
Sandor Kantor, PhD
Electrophysiology
Consulting
Services
Bridging preclinical and clinical development with 20+ years of expertise in neurophysiological biomarkers, pharmaco-EEG, and CNS drug discovery.
About
I am a translational neuroscientist with over 20 years of experience bridging basic research and drug development. My career has spanned prestigious academic institutions including Harvard Medical School and the University of Cambridge, as well as leadership roles in the pharmaceutical industry.
As former Scientific Director at a multinational preclinical CRO, I led international teams delivering neurophysiological biomarker programmes for major pharmaceutical companies and innovative biotech firms. My expertise centres on EEG methodology, pharmaco-EEG profiling, and the design of translational studies that de-risk CNS drug development.
I hold a PhD in Clinical Medicine and have authored over 20 peer-reviewed publications in leading journals including Brain, Sleep, and Neurotherapeutics. My research has been supported by over £270,000 in competitive funding.
20+
Years Experience
20+
Publications
£270K+
Research Funding
1500+
Citations
Therapeutic Area Expertise
Huntington's Disease
Depression
Anxiety
Schizophrenia
PTSD
Narcolepsy
Sleep Disorders
Epilepsy
Services
I offer specialist consulting services tailored to pharmaceutical companies, biotech firms, and academic research groups working in CNS drug discovery and neuroscience research.
System Implementation & Technical Support
Pharmaco-EEG Study Design
Data Analysis & Interpretation
Translational Biomarker Strategy
Disease Model Expertise
Ongoing Scientific Advisory
Representative Case Studies
Real-world examples of neurophysiological studies conducted across species and therapeutic areas.
Sleep-Wake Profiling Study
24-h wireless EEG/EMG recording in WKY rats after psilocybin
- Manual / semi-automatic vigilance state scoring
- Detailed REM sleep assessment and quantification
- Dose-dependent effect analysis
- Time-course hypnogram visualisation
Kantor S, Higgins L, Upton N, Duxon M; SFN.org Neurosci Meeting Planner P711.05 (2021)
Mismatch Negativity (MMN) Study
Pre-attentive auditory information processing after ketamine
- MMN as translational marker of schizophrenia
- ERP component elicited by deviant auditory stimuli
- Generated by temporo-frontal network activation
- Drug efficacy evaluation and mechanism validation
Kantor S, Laursen B, Upton N, Bastlund JF; SFN.org Neurosci Meeting Planner 610.04 (2019)
Selected Publications
A selection of peer-reviewed publications from over 20 papers spanning neurophysiology, sleep research, neurodegeneration, and CNS pharmacology.
Chronic paroxetine treatment prevents the emergence of abnormal EEG oscillations in Huntington's disease mice
Neurotherapeutics 4, 1120–1133
A single dose of hypnotic corrects sleep and EEG abnormalities in symptomatic Huntington's disease mice
Neuropharmacology 105, 298–307
Effects of the fatty acid amide hydrolase inhibitor URB597 on coping behavior under challenging conditions in mice
Psychopharmacology 231, 593–601
Get in Touch
Interested in discussing a project or exploring how I can support your research programme? I'd welcome the opportunity to hear about your needs.
Based in the United Kingdom. Available for remote consulting worldwide.
